Microneedling for Burn Scars
Burning scars can be devastating not only because of appearance defects, but also the mobility of the affected area and increased sensitivity. Various surgical procedures and dermatological treatments such as laser resurfacing, fractional laser, radiofrequency energy, chemical peel, and dermabrasion are used to treat surface irregularities, and discoloration to reduce the overall appearance of the scar and all the lines blend demarcation that contributes to visibility.
The effectiveness of the current range of therapies is mitigated by the associated disadvantages. On the one hand, ablative damage can easily exacerbate sensitivity, which is undesirable. In a way, the therapy mimics the original pathology responsible for scarring and can cause fibrosis and increased fibrosis and erosion of dermal papillae with repeated treatment. Also, depending on necrotic damage (due to trauma, ablation or coagulation of tissue) brings undesirable means such as over-stimulation of the inflammatory cascade.
Microneedle Percutaneous Collagen Induction (PCI) for burn scars can be an excellent method because of the epidermis, and surrounding tissue structures are largely left intact after the fractional microneedle treatment, and the induction of Collagen takes place in a more natural way of cell death due to controlled damage is due to apoptosis, a natural process in which the inflammatory cascade is limited and more effective. Wounding via serial fractional microneedle insertion stimulates the natural healing of micro-needles and cellular replacement reactions, but heals quickly, leading to a rapid restoration of the barrier function.
As growth factor zone is saturated, it increases fibroblast production and up to the activity is regulated, with subsequent proliferation and stimulation of keratinocytes. A natural network of healthy collagen is built from the bottom up, which is an essential aspect of successful healing. The epidermal tissue is spared, which is ideal for burn scars. In particular, Collapen micro-needle therapy can be used in personal settings, which are considered less appropriate for most procedures than that. The mechanism of action, the apoptotic induction of natural collagen networks, is independent of erosion or other adverse changes in treated tissue for repeated treatment.
This theoretical basis for the application of the micro-needle for healing burns seems to have been confirmed by early clinical studies. The results of a key study combining Topical Vitamins A and C with microneedle percutaneous collagen induction for burn scarring showed (by histological analysis after 12 months after PCI treatment) Regeneration/normalization of tissue healing and reduces the appearance of the scar after researchers and patients.
Sixteen patients (8 women) with scar after burn were pre-treated for at least one month with topical vitamins, were continued after treatment. A dermal medical grade roll was used to perform one, two or three treatments on each patient. No postoperative hypopigmentation, hyperpigmentation, increased scarring, or increased photosensitivity were recorded; Patient satisfaction with appearance improved significantly from baseline to 12-month follow-up.
A medical-grade dermal roller was used to perform one, two, or three treatments on each patient. No post-procedure hypopigmentation, hyperpigmentation, increased scarring, or increased photosensitivity was recorded; patient satisfaction with appearance improved significantly between baseline and final follow-up at 12 months. The study cited the theoretical importance of maintaining a healthy epidermis while performing repeated treatment to truly restore appearance.
Burn Scar Treatment – Microneedling or Collagen Induction Therapy has been shown to reduce the appearance of burn scars by 80%, with histologic evidence of increased collagen and elastin deposition and a 45% thickening of the dermis.